In 1992, she won the César Award for Most Promising Actress for her role in La neige et le feu, directed by Claude Pinoteau.
She had her first international success in the 1994 romantic comedy-drama film Don Juan DeMarco. The following year, she starred in Le Garçu, directed by Maurice Pialat, alongside Gérard Depardieu.
In 1999, she played in Peut-être, directed by Cédric Klapisch, with Jean-Paul Belmondo and Romain Duris.
In 2002, she played Christine Faure in the movie The Adversary, directed by Nicole Garcia, and starring Daniel Auteuil.
She was nominated two times for the César Award for Best Supporting Actress : in 2004, for The Cost of Living, directed by Philippe Le Guay and in 2014, for Young & Beautiful, directed by François Ozon.